Donald N. Serafano, M.D. was born and raised in Detroit, Michigan. He was awarded a four year academic scholarship to Villanova University in Philadelphia and graduated with a Bachelor of Science degree in Biology & Chemistry. He was awarded a second academic scholarship this time to Wayne State University School of Medicine in Detroit. Dr. Serafano completed his general internship in Internal Medicine at the Mayo Clinic in Rochester. After completing his studies Dr. Serafano served as a Captain and General Medical Officer of the United States Air Force. He received an honorable discharge before going on to complete his fellowship residency in the Department of Ophthalmology at the Mayo Clinic in Rochester.

Dr. Serafano moved to Long Beach, California for additional training in corneal surgery and intraocular lens implants. He has been practicing general ophthalmology with a special interest in cataracts, lens implants, refractive surgery and glaucoma since 1978. He is on the advisory board for the development of phacoemulsificaton (a method of small incision cataract removal), foldable lens implants and no stitch cataract surgery. Dr. Serafano has given many scientific presentations and performed live surgery at symposiums all over the world.

He is currently an Associate Clinical Professor at the University of Southern California. Dr. Serafano’s numerous awards include being listed as an Honored Professional in both the American Directory of Who’s Who in Executives and Business and The National Register’s Who’s Who in Executive and Professionals 2000 Edition. Dr. Serafano has also been selected by his peers to be included in the Best Doctors in America, Los Angeles Magazine’s "The Essential Guide to Los Angeles’ Best Doctors", and Orange Coast Magazine's "Guide to Best Doctors in Orange County". The American Academy of Ophthalmology recognized his achievements by giving him the Honor Award in 1996. He has served as President (1993-1994) of the Rotary Club of Long Beach, California.

Dr. Serafano is Board Certified by the American Academy of Ophthalmology. He has completed a Fellowship in LASIK surgery and was certified in the VISX Excimer Laser System in 1994.